BIOACTIVITY SCREENING AND ISOLATION OF THREE FATTY ACID ETHYL ESTERS FROM ANEMONIA VIRIDIS
نویسندگان
چکیده
منابع مشابه
Red blood cell fatty acid ethyl esters: a significant component of fatty acid ethyl esters in the blood.
Although alcohol abuse is known to cause an array of ethanol-induced red blood cell (RBC) abnormalities, the underlying molecular mechanisms remain poorly understood. Fatty acid ethyl esters (FAEEs) are toxic, nonoxidative ethanol metabolites that have been found in blood, plasma, and tissues. Because FAEEs have been shown to be incorporated into phospholipid bilayers, we conducted a controlled...
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Due to the relatively short half-lives of ethanol and its major metabolite, acetaldehyde, there has been intense search of more stable and reliable biological markers. Fatty acid ethyl esters (FAEE) are a group of ethanol metabolites that result from the enzymatic conjugation of free fatty acids or fatty acyl-CoA to ethanol. FAEE have been proposed as markers of recent and chronic ethanol consu...
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Fatty acid ethyl esters (FAEE), esterification products of fatty acid and ethanol, have been implicated as mediators of ethanol-induced organ damage. To understand the molecular and cellular events in FAEE synthesis and secretion, we developed a system in which HepG2 cells synthesize and release FAEE into the culture medium upon incubation with ethanol. The synthesis of FAEE was observed within...
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ژورنال
عنوان ژورنال: FARMACIA
سال: 2020
ISSN: 0014-8237
DOI: 10.31925/farmacia.2020.2.22